| 产品名称: |
Recombinant Mouse S100A15A |
| 产品形貌: |
Recombinant Mouse S100 Calcium Binding Protein A15A is produced by our E.coli expression system and the target gene encoding Met1-Tyr108 is expressed. |
| 卵白编号: |
Q6S5I3 |
| 分子量: |
12.9 KDa |
| 表观分子量: |
12 KDa, reducing conditions |
| 产品纯度: |
Greater than 95% as determined by reducing SDS-PAGE. |
| 内毒素: |
Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test. |
| 贮存条件: |
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles. |
| 运输条件: |
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below. |
| 研究配景: |
Members of the S100 protein family are involved in calcium- or zinc-dependent cellular functions and regulate immune-mechanisms, cell proliferation and differentiation. Some S100 members have been established as tumor markers because they are dysregulated during carcinogenesis. Psoriasin (S100A7) and koebnerisin (S100A15) are highly homologous proteins that have been first described in psoriasis, which is characterized by disturbed epidermal maturation and chronic inflammation. Several studies showed that the coexpression of the hS100A7 and hS100A15 in psoriasis suggests that both proteins participate in keratinocyte maturation, proliferation and/or skin inflammation. |
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