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Overview 文献(13)
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EBioMedicine
Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortality
日期：2024-11-01
IF：10.8
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Nano Research
Oral pyroptosis nanoinhibitor for the treatment of inflammatory bowel disease
日期：2023-07-31
IF：9.9
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Frontiers in Oncology
Downregulation of hsa_circ_0001836 Induces Pyroptosis Cell Death in Glioma Cells via Epigenetically Upregulating NLRP1
日期：2021-03-31
IF：4.848
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Clinical Epigenetics
Clinical significance and prognostic value of SIRT1 genetic variants in sepsis: a multicenter hospital-based case–control study
日期：2025-07-21
IF：4.4
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BIOMEDICINES
Necroptotic and Apoptotic Pathways in Sepsis: A Comparative Analysis of Pediatric and Adult ICU Patients
日期：2025-07-14
IF：3.9
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Cardiovascular Toxicology
Thiolutin Alleviates Cardiotoxic Effects of Doxorubicin by Suppressing NLRP3 Inflammasome in the Mouse Model
日期：2024-12-11
IF：3.4
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NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Ruminococcaceae promotes the NLRP3/ASC/Caspase-1 axis–mediated pyroptotic signaling in papillary thyroid carcinoma by upregulating RBM15 to increase the N6-methyladenosine methylation modulation of NLRP3
日期：2026-02-02
IF：3.1
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EXPERIMENTAL BIOLOGY AND MEDICINE
The correlation between pro- and anti-inflammatory cytokines and anti-spike IgG antibody responses induced by the SARS-CoV-2 coronavirus vaccine
日期：2026-01-14
IF：2.8
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ASIAN JOURNAL OF ANDROLOGY
NLRP3 activation by lipopolysaccharide (LPS) mediates the pyroptosis of human spermatogonial stem cells via GBP4 regulation
日期：2026-01-16
IF：2.7
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EXPERIMENTAL BIOLOGY AND MEDICINE
The correlation between proand anti-inflammatory cytokines and anti-spike IgG antibody responses induced by the SARS-CoV-2 coronavirus vaccine
日期：2025-12-14
IF：2.7
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Open Medicine
ANO6 (TMEM16F) inhibits gastrointestinal stromal tumor growth and induces ferroptosis
日期：2024-05-15
IF：2.1
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Cell Biochemistry and Biophysics
The Impact of Liraglutide, a GLP-1 Receptor Agonist, on High Glucose-Induced Inflammation, Apoptosis, Oxidative Stress, and NLRP3 Signaling
日期：2025-04-11
IF：1.8
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Artery Research
Correlation of NLRP3 and Downstream Inflammatory Factors in Patients with Different Types of Coronary Heart Disease
日期：2025-12-16
IF：1.6
标准曲线
| Concentration (pg/mL) | OD | Corrected OD |
|---|---|---|
| 8000.00 | 2.074 | 1.959 |
| 4000.00 | 1.622 | 1.507 |
| 2000.00 | 1.273 | 1.158 |
| 1000.00 | 0.968 | 0.853 |
| 500.00 | 0.542 | 0.427 |
| 250.00 | 0.356 | 0.241 |
| 125.00 | 0.217 | 0.102 |
| 0.00 | 0.115 | 0.000 |
细密度
板内细密度（测定内的细密度）：CV%<8%
三个已知浓度的样品划分在1个酶标板上测试20次，，，以评估剖析板内细密度。。
板间细密度（测定板间间细密度）：CV%<10%
三个已知浓度的样品划分在3个差别的酶标板上测试40次，，，以评估剖析板间的细密度。。
接纳率
划分往差别样本中添加已知浓度的人 IL18，，，
做接纳率实验，，，得出接纳率规模清静均接纳率
| 样本类型 | 接纳率规模 | 平均接纳率 |
|---|---|---|
| 血清(n=5) | 87-95% | 91% |
| EDTA 血浆(n=5) | 78-92% | 85% |
| Heparin 血浆(n=5) | 92-106% | 99% |
线性
将添加有人 IL18的样天职别稀释2倍，，，4倍，，，8倍，，，16倍做接纳实验，，，得出接纳率规模
| 样本类型 | 1:2 | 1:4 | 1:8 | 1:16 |
|---|---|---|---|---|
| 血清(n=5) | 86-93% | 91-104% | 87-98% | 95-99% |
| EDTA 血浆(n=5) | 89-99% | 83-95% | 88-94% | 96-101% |
| Heparin 血浆(n=5) | 85-100% | 84-98% | 95-101% | 88-102% |
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