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Overview 文献(10)
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International Journal of Biological Sciences
DHCR24 Deficiency Drives Age-Related Meibomian Gland Dysfunction by Regulating Lipid Metabolic Imbalance and Cytosolic mtDNA-Induced cGAS-STING Activation
日期：2026-03-26
IF：10
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International Immunopharmacology
IL-17A drives cognitive aging probably via inducing neuroinflammation and theta oscillation disruption in the hippocampus
日期：2022-05-31
IF：5.714
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Biochemical Pharmacology
Artesunate reduces oxidative stress and inflammation in NAFLD by activating the Nrf2 pathway
日期：2026-01-26
IF：5.6
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Journal of Ethnopharmacology
Jianpi Antai formula prevents miscarriage by repressing M1 polarization of decidual macrophages through ubiquitination of NLRP3 mediated by MARCH7
日期：2024-01-18
IF：5.4
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European Journal of Pharmacology
Empagliflozin inhibits autophagy and mitigates airway inflammation and remodelling in mice with ovalbumin-induced allergic asthma
日期：2023-03-28
IF：5
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Scientific Reports
Tofacitinib and metformin reduce the dermal thickness and fibrosis in mouse model of systemic sclerosis
日期：2022-02-15
IF：4.996
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iScience
Behenic acid alleviates inflammation and insulin resistance in gestational diabetes mellitus by regulating TLR4/NF-κB signaling pathway
日期：2024-10-18
IF：4.6
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Journal of Virology
An intranasal influenza virus vector vaccine protects against Helicobacter pylori in mice
日期：2024-02-15
IF：4
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BIOSCIENCE REPORTS
Protective effects of oxymatrine against DSS-induced acute intestinal inflammation in mice via blocking the RhoA/ROCK signaling pathway
日期：2019-07-19
IF：3.84
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International Journal of Ophthalmology
Ragweed pollen induces allergic conjunctivitis immune tolerance in mice via regulation of the NF-κB signal pathway
日期：2021-07-18
IF：1.779
标准曲线
| Concentration (pg/mL) | OD | Corrected OD |
|---|---|---|
| 500.00 | 2.204 | 2.120 |
| 250.00 | 1.700 | 1.616 |
| 125.00 | 1.146 | 1.062 |
| 62.50 | 0.752 | 0.668 |
| 31.25 | 0.593 | 0.509 |
| 15.63 | 0.302 | 0.218 |
| 7.82 | 0.172 | 0.088 |
| 0.00 | 0.084 | 0.000 |
细密度
板内细密度（测定内的细密度）：CV%<8%
三个已知浓度的样品划分在1个酶标板上测试20次，，，，，以评估剖析板内细密度。。。。。
板间细密度（测定板间间细密度）：CV%<10%
三个已知浓度的样品划分在3个差别的酶标板上测试40次，，，，，以评估剖析板间的细密度。。。。。
接纳率
划分往差别样本中添加已知浓度的小鼠 IL17，，，，，
做接纳率实验，，，，，得出接纳率规模清静均接纳率
| 样本类型 | 接纳率规模 | 平均接纳率 |
|---|---|---|
| 血清(n=5) | 85-97% | 91% |
| EDTA 血浆(n=5) | 97-105% | 101% |
| Heparin 血浆(n=5) | 83-99% | 95% |
线性
将添加有小鼠 IL17的样天职别稀释2倍，，，，，4倍，，，，，8倍，，，，，16倍做接纳实验，，，，，得出接纳率规模
| 样本类型 | 1:2 | 1:4 | 1:8 | 1:16 |
|---|---|---|---|---|
| 血清(n=5) | 92-105% | 82-92% | 86-94% | 81-95% |
| EDTA 血浆(n=5) | 92-105% | 92-101% | 80-94% | 86-101% |
| Heparin 血浆(n=5) | 85-95% | 79-96% | 89-101% | 85-97% |
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